Red Sox vs Brewers Picks and Prediction – 5/28/2025

American Family Field will play host to a Wednesday afternoon MLB interleague clash between the Boston Red Sox and the Milwaukee Brewers. Be ready for the baseball season with all of our MLB predictions. The Red Sox (27-30) have dropped 16 of their first 27 road games and are eight games off the pace in the AL East Division race. Last night, Boston batters went 1-for-10 with runners in scoring position during a 5-1 road loss in ten innings against Milwaukee.

Twenty-six year old righty Brayan Bello (2-1 4.08 ERA) will head to the hill for the Red Sox in this contest. Last time out, Bello (4 IP) gave up two runs and fanned seven batters during a 19-5 home victory versus Baltimore. 

The Milwaukee Brewers are riding a three-game winning streak and are six games out first place in the NL Central Division. On Tuesday, Christian Yelich sent the Milwaukee fans home in a frenzy with a walk-off grand slam. SP Aaron Civale allowed one run in five innings and did not factor in the decision for the Brewers (28-28), who improved to 17-10 at home. 

Milwaukee manager Pat Murphy will give the nod to talented right-hander Freddy Peralta (5-3 2.55 ERA) on Wednesday. In four home starts this season, Peralta is 3-0 and has allowed just two runs across 24 innings. 

Boston 3B Alex Bregman has landed on the 10-day injured list with a quad injury and could miss more than a month. Through 57 games, Boston ranks 5th in OPS and 6th in runs scored. For the season, Milwaukee ranks 25th in OPS and 12th in runs scored. Take the over. Final Score Prediction, Milwaukee Brewers win 6-4.