Red Sox vs Tigers Picks and Prediction – 5/12/2025

In Monday night MLB action, the Boston Red Sox will travel to Comerica Park to take on the Detroit Tigers. Be ready for the baseball season with all of our MLB predictions. The Red Sox (22-20) have split their first 22 road games and trail AL East Division leading New York by two games. On Sunday, SP Lucas Giolito (1-1) allowed one unearned run across six plus frames to lead Boston to a 3-1 road victory against Kansas City. 

Twenty-eight year old righty Tanner Houck (0-2 6.10 ERA) will take the mound for the Red Sox in this matchup. Last time out, Houck (4.1 IP) gave up six hits and three runs (2 ER) during a 6-4 home victory versus Texas. 

The Detroit Tigers have won 14 of their first 19 home games and hold a two-game lead over Cleveland for the top spot in the AL Central Division. On Sunday, Detroit batters were limited to four hits and struck out ten times during a 6-1 home loss versus Texas. SP Reese Olson (4-3) gave up three runs in four innings and took the loss for the Tigers, who fell to 26-15 on the year.

Rookie right-hander Jackson Jobe (2-0 4.88 ERA) will make his seventh career major league start. The Tigers are undefeated in Jobe’s six starts and have provided plenty of support with 39 runs over that stretch. 

Boston SP Walker Buehler (shoulder) is on the 15-day injured list and is expected to return next week. Through 42 games, Boston ranks 7th in OPS and 6th in runs scored. For the season, Detroit ranks 6th in OPS and 4th in runs scored. Take the over. Final Score Prediction, Detroit Tigers win 6-5.