Red Sox vs White Sox Picks and Prediction – 4/11/2025

On Friday, the Boston Red Sox (6-6) face off against the Chicago White Sox (2-8) at Rate Field in Chicago, Illinois. Keep up to date with all the MLB action, with our expert MLB picks.

Chicago comes into this matchup on a six-game losing streak prior to their series finale against Cleveland and series opener against Boston. In their 1-0 defeat against Cleveland, Shane Smith delivered an impressive performance for the White Sox, pitching six innings and giving up just two hits and one walk without surrendering any runs. This season, Nick Maton and Andrew Benintendi have been power hitters for Chicago, each having hit two home runs. Close behind are Austin Slater, Lenyn Sosa, Andrew Vaughn, Michael A. Taylor, and Brooks Baldwin, each contributing one home run. Andrew Benintendi also stands out as Chicago’s top RBI producer, accumulating six RBIs this season. He leads the team with a batting average of .290. Over the last five games, the White Sox have struggled defensively, allowing an average of five runs and finding themselves at the bottom of the AL Central Division standings. They hope to improve their record in the upcoming home series against the Red Sox. So far, Chicago is averaging 3.2 runs per game.

Boston enters this game on a two-game losing streak, but has won three of their last five games prior to their last two games of their series against Toronto. In a 6-1 defeat against Toronto, Garrett Crochet pitched for 5.2 innings, giving up five hits, four walks, and one earned run for the Red Sox. This season, Wilyer Abreu is Boston's home run leader with three homers. Meanwhile, Alex Bregman, Trevor Story, and Kristian Campbell each have hit two home runs, tying them as the team’s second-highest scorers in that category. Abreu is also leading in RBIs with twelve and boasts the highest batting average on the team at .412. In their last five games, Boston has averaged 7.8 runs per game and is currently one game behind both the Yankees and Blue Jays in the race for the top spot in the AL East Division. The Red Sox aim to capitalize on Chicago's early struggles as they head to the South Side for a win. Overall, the team is averaging 5.5 runs per game this season.

The White Sox have struggled at the start of the season, losing eight of their first ten games. They're hoping to break this losing streak as they host the Boston Red Sox in Chicago. Meanwhile, Boston has had a balanced beginning, winning half of their first twelve matchups, and they're aiming to maintain their strong offensive performance. On the mound, Boston's starting pitcher, Sean Newcomb, comes in with a record of 0-1 and an ERA of 5.19. Chicago’s starter, Davis Martin, is also 0-1, but with a slightly higher ERA of 5.73. Final Score Prediction, Boston Red Sox win 9-7.