Red Sox vs White Sox Picks and Prediction – 4/13/2025

Boston (7-8) heads to Rate Field for a Saturday afternoon rematch with the White Sox (3-10) after getting pummeled 11-1 on Friday. Garrett Crochet (1-1, 1.45 ERA) takes the mound for Chicago, facing off against Boston’s Shane Smith (0-0, 1.54 ERA). Both lefties have looked sharp early, but Boston needs to bounce back after a brutal loss, while the struggling White Sox aim to keep momentum at home. Elevate your MLB game with our top-notch MLB picks.

The Red Sox are on a 1-4 slide after that lopsided series opener. Boston’s lone recent win came in extras over Toronto, but offensive inconsistency has been the story. One day they push four runs across in 10 innings, the next they can barely touch home. Shane Smith has been a bright spot in the rotation, giving up only 4 hits across 11.2 innings with a stellar 0.77 WHIP. The lineup leans on Wilyer Abreu, who's hitting .364 with 3 homers and a .481 OBP, while Alex Bregman has driven in 12 runs with a .290 average.

On the mound, Boston has been mediocre, allowing 3.96 runs per game with a 1.38 WHIP. Injuries are starting to pile up: Giolito, Crawford, and Bello are all shelved, and Masataka Yoshida’s absence leaves a hole in left field. Still, the Red Sox have a more complete staff than Chicago, especially in bullpen depth. The team batting average sits at .252, with 132 hits and 11 long balls. 

The White Sox finally snapped an ugly skid with Friday’s 11-run explosion, the first win in six games. Lenyn Sosa and Andrew Benintendi have been the offensive pulse, though Benintendi (2 HR, .290 AVG) is currently on the IL. That victory was huge for morale, but with just 87 hits and a .211 team average, offensive consistency is a big question mark. 

Defensively, Chicago’s 3.72 team ERA is slightly better than Boston’s, but the Sox have allowed more walks (52) and have just 103 strikeouts. Injuries are hitting hard here too, with Benintendi, Rojas, and three others out. They’ve been miserable at home (3-4) and worse in day games (3-8), and the .217 opponent batting average suggests they aren’t making it easy on foes, even in losses. 

Boston’s offense has more proven production, and Shane Smith has been nails so far. Chicago might’ve had a huge night Friday, but with Benintendi out and still hitting just .211 as a team, trusting one game is risky. Boston has a clear edge in consistency and firepower, and Smith can go toe-to-toe with Crochet. Final Score Prediction: Boston Red Sox win 4-2.