Orioles vs Blue Jays Picks and Prediction – 3/28/2025

By: David Anicetti |

Last Updated: 03/27/2025 at 7:58 PM ET

Baltimore Orioles at Toronto Blue Jays 03/28/25 - MLB Picks & Predictions
Game Start: 3/28/2025, 11:07 PM UTC
Latest Odds: TOR -130 ; O/U 8.5

Orioles vs Blue Jays Prediction

The Baltimore Orioles play the second game of a four-game series on the road Friday versus the Toronto Blue Jays. Baltimore had a very strong season in 2024, finishing second in the American League East at 91-71, after leading or tying for the lead during most of the regular season. Baltimore has returning players from last season and a scattering of new faces on the roster for 2025. Keep up to date with all the MLB action with our MLB predictions.

Cedric Mullins, Adley Rutschman, Ryan Mountcastle, and last season's star Gunnar Henderson return. Henderson is sidelined at this time with an injury. Tyler O'Neill joined Baltimore from Boston and gives the Orioles another strong bat at the plate and a solid player in the outfield. Baltimore will start off-season acquisition Charlie Morton on the mound Friday. Last season with Atlanta, the right-hander was 8-10 with a 4.19 ERA, 167 Ks, and 65 BBs.

Toronto finished its regular season in 2024 last in the American League East at 74-88. Toronto struggled on the mound last season with a team ERA of 4.29 and a WHIP of 1.27. At the plate, Toronto performed below average with a batting average of .241 and a slugging percentage of. .389. The Blue Jays have plenty of players returning from last season, as well as new acquisitions they hope will help them become contenders once again.

The batting order will be difficult for opposing pitchers, as Vladimir Guerrero Jr returns along with Bo Bichette, George Springer, and Daulton Varsho. Toronto acquired right fielder Anthony Santander from Baltimore. The Blue Jays signed Max Scherzer, and the veteran will give the Blue Jays plenty of experience and talent on the mound. Toronto will send Kevin Gausman to the mound on Friday. Last season, the right-hander was 14-11 with a 3.83 ERA, 162 Ks, and 56 BBs.

Orioles vs Blue Jays Pick Analysis

The Baltimore Orioles will win in the second game of this four-game series on Friday when visiting the Toronto Blue Jays. Baltimore ended last season with five victories in its last six games on the road. The Orioles have a strong lineup that will produce plenty of runs to help the pitching staff. Baltimore starter Charlie Morton is an experienced right-hander who will keep Toronto's batting order in check on Friday. Final Score Prediction, Baltimore Orioles win 5-2.

Our Free MLB Pick for Toronto Blue Jays vs Baltimore Orioles

Baltimore Orioles +110