Orioles vs Yankees Picks and Prediction – 6/22/2025

The Sunday MLB schedule will get underway with a matinee between the Baltimore Orioles and the New York Yankees. Be ready for the baseball season with all of our MLB predictions. The Orioles (33-43) are seven games below .500 on the road and are trapped in the AL East Division basement. On Saturday, Baltimore SP Zach Eflin (3 IP) was rocked for ten hits and six runs during a 9-0 road loss against New York.

Twenty-nine year old righty Dean Kremer (6-7 4.80 ERA) will make his 15th start of the year for the Orioles. Last time out, Kremer (5 IP) allowed four hits and one run during a 5-1 road victory against Tampa Bay. 

The New York Yankees have dropped seven of their previous ten games and are clinging to a 1.5 game lead over Tampa Bay for first place in the AL East Division. During yesterday’s home victory, SS Anthony Volpe went 3-for-4 with one of New York’s four home runs. SP Clarke Schmidt (4-3) was pulled after seven hitless innings and earned the win for the Yankees (44-32), who improved to 23-16 at home. 

The Yankees will counter with twenty-six year old righty Will Warren (4-4 4.83 ERA) in the series finale. In his last start, Warren (6 IP) gave up three runs and fanned 11 batters during a 4-0 home loss versus Los Angeles. 

Baltimore C Adley Rutschman (oblique) has landed on the 10-day injured list for the first time in his career. Through 76 games, Baltimore ranks 18th in OPS and 23rd in runs scored. For the season, New York ranks 2nd in OPS and 4th in runs scored. Take the over. Final Score Prediction, New York Yankees win 7-5.