Orioles vs Twins Picks and Prediction – 5/8/2025

The Thursday MLB schedule will get underway with a matinee between the Baltimore Orioles and the Minnesota Twins from the Target Center. Be ready for the baseball season with all of our MLB predictions. The Orioles (13-21) are seven games below .500 on the road and are trapped in the AL East Division cellar. Last night, Baltimore OF Ramon Laureano homered and scored twice during a 5-2 road loss against Minnesota.

Twenty-nine year old righty Dean Kremer (3-4 5.73 ERA) will make his eighth start of the year for the Orioles. Last time out, Kremer fired seven shutout frames and allowed just three hits during a 3-0 home victory versus Kansas City. 

The Minnesota Twins have won 11 of their first 17 home games and are 6.5 games off the pace in the AL Central Division standings. During Wednesday’s home victory, OF Byron Buxton staked Minnesota to the lead with a three-run blast in the third inning. Jhoan Duran struck out the side to earn the save for the Twins, who improved to 17-20 overall.

Minnesota manager Rocco Baldelli will turn to talented right-hander Joe Ryan (2-2 2.93 ERA) on Thursday. Through 40 innings of work, Ryan has retired 47 batters by strikes and owns a minuscule 0.90 WHIP.

Baltimore OF Tyler O’Neill (neck) was scheduled to start a rehab assignment on Tuesday with Triple-A Norfolk. Through 35 games, Baltimore ranks 22nd in OPS and 23rd in runs scored. For the season, Minnesota ranks 20th in OPS and 18th in runs scored. Take the Orioles to win on the road. Baltimore Orioles win 5-3.