Orioles vs Red Sox Picks and Prediction – 5/25/2025

AL East Division rivals will square off on Sunday afternoon, when the Baltimore Orioles take on the Boston Red Sox from Fenway Park. Be ready for the baseball season with all of our MLB predictions. The Orioles (17-34) have dropped 19 of their first 28 road games and are trapped in the division cellar. In the second game of yesterday’s doubleheader, OF Dylan Carlson delivered a run-scoring double in the ninth inning to lift Baltimore to a 2-1 road victory. 

Twenty-nine year old righty Dean Kremer (3-5 5.50 ERA) will make his 11th start of the year. The Orioles have dropped Kremer’s previous three starts and he has surrendered ten runs across his last 18 frames. 

The Boston Red Sox are three games above .500 at home and trail first place New York by 5.5 games. In the opening game of Saturday’s doubleheader, Boston walked it off in the tenth inning on a Rafael Devers single that scored Ceddanne Rafaela. Jarren Duran, Wilyer Abreu, and Abraham Toro all homered for the Red Sox (27-27). 

Boston manager Alex Cora will give the nod to thirty year old righty Walker Buehler (4-1 4.00 ERA) on Sunday. Through 36 innings of work, Buehler has struck out 33 batters and owns a solid 1.19 WHIP.

Baltimore OF Ramon Laurean has been placed on the 10-day injured list with a left ankle sprain. Through 51 games, Baltimore ranks 22nd in OPS and 25th in runs scored. For the season, Boston ranks 5th in OPS and 5th in runs scored. Take the Red Sox to win at home. Final Score Prediction, Boston Red Sox win 6-4.