Orioles vs Red Sox Picks and Prediction – 5/23/2025

The Baltimore Orioles play the second game of a four-game series on the road Friday versus the Boston Red Sox. Baltimore is 16-32 following its 8-4 victory over the Milwaukee Brewers on Wednesday, snapping an eight-game losing streak. Baltimore is last in the American League East, 13 games behind the first-place New York Yankees. Keep up to date with all the MLB action with our expert MLB picks.

Ryan O'Hearn is batting .306 with a .396 on-base percentage to lead Baltimore in both categories. Cedric Mullins is the leader in home runs with 10 and RBI with 31, while Gunnar Henderson is the leader in hits with 43. Baltimore is batting .232 with a .387 slugging percentage. On Friday, Baltimore will send Charlie Morton to the mound. The right-hander is 0-7 with a 7.68 ERA, 40 Ks, and 24 BBs.

The Boston Red Sox dropped to 25-26 following Wednesday’s 5-1 loss to the New York Mets. Nevertheless, Boston won two out of three over the National League East-leading Mets, and the Red Sox have won three of the last five. Boston is 10th in team batting average, and the Red Sox are 18th in team ERA. Boston is third in the AL East, 5 ½ games behind the Yankees.

Alex Bregman is batting .297 with 11 home runs and 58 hits, to lead Boston in the three categories. Rafael Devers is the leader in RBI with 39 and on-base percentage at .409. Boston is batting .252 with a .419 slugging percentage. On Friday, the Boston Red Sox will send Brayan Bello to the mound. The right-hander is 2-1 with a 4.02 ERA, 20 Ks, and 19 BBs.

Boston will win at home on Friday when hosting Baltimore, but the play here is OVER. The OVER has cashed in four of Baltimore's last five and nine of the last 12 Baltimore has played on the road versus Boston. Baltimore starter Charlie Morton has had three consecutive relief appearances, allowing two runs on four hits across 9.1 innings. Boston starter Brayan Bello was hit hard last time out, allowing seven runs on seven hits across 4.1 innings. Final Score Prediction: Boston Red Sox win, but our best play is OVER 7-5.