Orioles vs Diamondbacks Picks and Prediction – 4/9/2025

The Baltimore Orioles conclude a three-game series on the road Wednesday versus the Arizona Diamondbacks. Baltimore is 5-6 and 4th in the American League East, 1 ½ games behind the first-place New York Yankees. Baltimore defeated Arizona 5-1 on Monday in the opening game of the series. The Orioles have won two of the last three. Keep up to date with all the MLB action with our expert MLB picks.

Tyler O'Neill is batting .333 to lead Baltimore. Cedric Mullins is the leader in home runs with three, RBI with 12, and on-base percentage at .419. Ryan Mountcastle is the leader in hits with 12. Baltimore has a team batting average of .259 and a slugging percentage of .414. On Wednesday, Baltimore will send Dean Kremer to the mound. The right-hander is 1-1 with a 6.52 ERA, 7 Ks, and 2 BBs.

The Arizona Diamondbacks dropped to 5-6 following Monday’s four-run loss to Baltimore. Arizona is 4th in the National League West, four games behind the first-place San Diego Padres. Arizona has lost each of its last three, and the Diamondbacks have dropped four of the last five. Arizona has scored the sixth most runs but is 27th in team ERA at 5.06.

Geraldo Perdomo is batting .308 with 12 RBI to lead Arizona in both categories. Eugenio Suarez is the leader in home runs with five. Josh Naylor is the leader in hits with an on-base percentage of .391. Arizona has a team batting average of .253 and a slugging percentage of .431. On Wednesday, Arizona will send Brandon Pfaadt to the mound. The right-hander is 1-1 with a 5.25 ERA, 9 Ks, and 1 BBs.

Arizona will win on Wednesday when hosting Baltimore, but the play here is OVER. The OVER has cashed in nine of Baltimore's last 13 on the road and four of Baltimore's last six head-to-head versus Arizona. Baltimore starter Dean Kremer has struggled in two outings, allowing seven runs across 9.2 innings. Arizona starter Brandon Pfaadt has allowed seven runs across 12 innings. Final Score Prediction, Arizona Diamondbacks win but our best play is OVER 7-5.