Diamondbacks vs Nationals Picks and Prediction – 4/4/2025

The Arizona Diamondbacks (4-2) will face the Washington Nationals (1-5) at Nationals Park on Friday, April 4, 2025, with first pitch scheduled for 6:45 PM ET. Both teams are looking to set the tone in this early-season matchup.​ Get in on all the action with our free MLB picks.

The Diamondbacks have started the season strong, boasting a 4-2 record. Offensively, they have been productive, with key contributions from players like Ketel Marte (.292 AVG). On the mound, right-hander Brandon Pfaadt is slated to start. Pfaadt delivered a quality start in his season debut but took the loss. He aims to build on that performance and secure his first win of the season.​

The Nationals have had a challenging start to the season, holding a 1-5 record. They are looking to rebound and find consistency both offensively and defensively. Keibert Ruiz has been the leader on offense, posting a .381 batting average and 2 home runs to begin the season. Right-hander Jake Irvin is expected to take the mound for Washington. In his season debut, Irvin pitched 5 innings, allowing 2 runs and striking out 2 batters. The Nationals will rely on him to deliver a strong performance to help turn their early season around.​

This matchup presents an opportunity for the Diamondbacks to continue their strong start and for the Nationals to begin a turnaround early in the season. Ultimately, we will go with the better offense and starter on the mound, and take the Diamondbacks to win this one by a score of 5-3.