Diamondbacks vs Giants Picks and Prediction – 5/14/2025

Beautiful Oracle Park will play host to a Wednesday afternoon MLB matchup between the Arizona Diamondbacks and the San Francisco Giants. Be ready for the baseball season with all of our MLB predictions. The Diamondbacks (22-21) are two games above .500 on the road and are sitting in fourth place in the NL West Division standings. Last night, Arizona SP Brandon Pfaadt (6-3) gave up four runs in four innings during a 10-6 road loss against San Francisco. 

Thirty-two year old southpaw Eduardo Rodriguez (1-3 6.86 ERA) is trying to find his groove. The Diamondbacks have dropped three of Rodriguez’s last four starts and he has surrendered 24 runs (21 ER) over that stretch.

The San Francisco Giants have won 13 of their first 19 home games and trail NL West Division leading Los Angeles by three games. During Tuesday’s home victory, 2B Christian Koss crushed a grand slam and SS Willy Adames added a two-run shot to power the San Francisco offense. SP Robbie Ray struck out nine batters in six innings to improve to 6-0 for the Giants (25-18).

Twenty-eight year old righty Jordan Hicks (1-4 5.82 ERA) shows flashes of potential for the Giants, but struggles to put it all together. Last time out, Hicks (6 IP) gave up three runs and struck out six batters during a 3-1 road loss against Minnesota. 

Arizona SP Jordan Montgomery (elbow) has been transferred to the 60-day injured list and is not eligible to return until July. Through 43 games, Arizona ranks 4th in OPS and 5th in runs scored. For the season, San Francisco ranks 20th in OPS and 12th in runs scored. Take the Giants to win at home. Final Score Prediction, San Francisco Giants win 5-3.