Diamondbacks vs Phillies Picks and Prediction – 5/4/2025

By: David Anicetti |

Last Updated: 05/03/2025 at 9:10 PM ET

Arizona Diamondbacks at Philadelphia Phillies 05/04/25 - MLB Picks & Predictions
Game Start: 5/4/2025, 6:05 PM UTC
Latest Odds: PHI -135 ; O/U 9

Diamondbacks vs Phillies Prediction

The Arizona Diamondbacks complete a three-game series on the road Sunday versus the Philadelphia Phillies. Arizona dropped to 17-15 following its 3-2 loss to Philadelphia in the opening game of the series on Friday, snapping a two-game winning streak by the Diamondbacks. Arizona is fourth in the National League West, five games behind the first-place Los Angeles Dodgers. Keep up to date with all the MLB action with our MLB picks.

Josh Naylor is batting .316 with a .391 on-base percentage to lead Arizona in both. Eugenio Suarez is the leader in home runs with 10, and Geraldo Perdomo is the leader in RBI with 26. Corbin Carroll has a team-high of 39 hits. On Sunday, the Arizona Diamondbacks will send Eduardo Rodriguez to the mound. The left-hander is 1-3 with a 6.06 ERA, 35 Ks, 8 BBs.

The Philadelphia Phillies improved to 18-14 following Friday’s one-run victory. Kyle Schwarber and Max Kepler each hit solo homers for Philadelphia in the 7th inning. The Phillies have won five of the last six, since snapping a five-game losing skid. Philadelphia is second in the National League East, 3 ½ games behind the first-place New York Mets.

Trea Turner is batting .299 with 35 hits to lead Philadelphia in both categories. Kyle Schwarber is the leader in home runs with 10, RBI with 25, and on-base percentage at .400. Philadelphia is batting .250 with a .386 slugging percentage. On Sunday, Philadelphia will send Ranger Suarez to the mound. The left-hander will make his season debut for the Phillies on Sunday. 

Diamondbacks vs Phillies Pick Analysis

The Philadelphia Phillies will win on Sunday when hosting the Arizona Diamondbacks, but the play here is OVER. The OVER has cashed in six of Arizona's last nine and 11 of Philadelphia's last 17. Arizona starter Eduardo Rodriguez has been hit hard in two consecutive outings, allowing 12 runs on 15 hits across 10.2 innings. Philadelphia starter Ranger Suarez will be making his season debut. Final Score Prediction: Philadelphia Phillies win but our best play is OVER 8-3.

Our Free MLB Pick for Philadelphia Phillies vs Arizona Diamondbacks

Over 9