Diamondbacks vs Marlins Picks and Prediction – 4/16/2025

By: David Anicetti |

Last Updated: 04/15/2025 at 7:28 PM ET

Arizona Diamondbacks at Miami Marlins 04/16/25 - MLB Picks & Predictions
Game Start: 4/16/2025, 10:40 PM UTC
Latest Odds: ARI -160 ; O/U 8

Diamondbacks vs Marlins Prediction

The Arizona Diamondbacks play the second game of a three-game series on the road versus the Miami Marlins. Arizona is 9-7 following its 5-2 victory over the Milwaukee Brewers on Sunday. Arizona won two out of three over the Brewers, and the Diamondbacks have won four of the last five. Arizona trails first-place San Diego in the National League West by 4 ½ games. Keep up to date with all the MLB action with our expert MLB picks.

Geraldo Perdomo is batting .333 with 13 RBI and an on-base percentage of .448 to lead Arizona in the three statistics. Eugenio Suarez is the leader in home runs with five, and Corbin Carroll is the leader in hits with 21. On Wednesday, the Arizona Diamondbacks will send Brandon Pfaadt to the mound. The right-hander is 2-1 with a 3.50 ERA, 12 Ks, and 3 BBs.

The Miami Marlins improved to 8-7 following Sunday’s 11-4 victory over the Washington Nationals. Matt Mervis hit a three-run home run for the Marlins in the 7th inning. Miami won two out of three in its series over the weekend versus Washington. The Marlins are third in the National League East, 2 ½ games behind the first-place Philadelphia Phillies.

Kyle Stowers is batting .314 with an on-base percentage of .410 to lead Miami in both statistics. Matt Mervis is the leader in home runs with five and in RBI with 11. Xavier Edwards is the leader in hits with 18. Miami is batting .253 with a .375 slugging percentage. On Wednesday, Miami will send Max Meyer to the mound. The right-hander is 1-1 with a 2.00 ERA, 19 Ks, and 5 BBs.

Diamondbacks vs Marlins Pick Analysis

Miami will win at home on Wednesday when hosting Arizona, but the play here is UNDER. The UNDER has cashed in four of Arizona's last six and nine of the last 12 that Arizona has played head-to-head versus the Diamondbacks. Arizona starter Brandon Pfaadt is coming off a solid outing in which the right-hander allowed no runs on four hits across six innings. Miami's Max Meyer gave up no runs on two hits across 6.1 innings last Wednesday versus the Mets. Final Score Prediction: Miami Marlins win but our best play is UNDER 4-2.

Our Free MLB Pick for Miami Marlins vs Arizona Diamondbacks

Under 8