Diamondbacks vs White Sox Picks and Prediction – 6/24/2025

The Arizona Diamondbacks play the second game of a three-game series on the road Tuesday versus the Chicago White Sox. Arizona dropped to 39-38 following Sunday’s 4-2 loss to the Colorado Rockies, snapping a three-game winning streak by the Diamondbacks. Arizona is fourth in the National League West, 10 games behind the first-place Los Angeles Dodgers. Keep up to date with all the MLB action with our MLB picks.

Josh Naylor is batting .303 to lead Arizona and has team highs in hits with 86 and on-base percentage at .358. Eugenio Suarez is the leader in home runs with 25 and RBI with 67. Arizona is batting .255 with a .448 slugging percentage. On Tuesday, Arizona will send Ryne Nelson to the mound. The right-hander is 4-2 with a 3.88 ERA, 45 Ks, and 18 BBs.

The Chicago White Sox improved to 25-53 following Sunday’s 4-2 victory over the Toronto Blue Jays. Miguel Vargas hit an RBI double in the eighth inning to put Chicago ahead for good. Chicago has won two out of the last three, but the White Sox prior to that had lost eight straight. Chicago trails first place in the American League Central by 23 ½ games.

Miguel Vargas is batting .243 with 10 home runs, 34 RBI, 67 hits, and an on-base percentage of .323 to lead Chicago in each of the five categories. Vargas is the only player for Chicago with double digits in home runs. Chicago is batting .221 with a .343 slugging percentage. On Tuesday, the Chicago White Sox will send Sean Burke to the mound. The right-hander is 3-7 with a 4.50 ERA, 61 Ks, and 35 BBs.

Both starting pitchers have performed well of late, but the advantage here goes to Arizona, which has performed better this season than Chicago. Arizona has won eight of its last 12, while Chicago has lost nine of its last 11. Arizona starter Ryne Nelson has had two straight solid outings, allowing one run on seven hits across 10.2 innings. Chicago starter Sean Burke pitched well last time out, allowing one run on four hits across 5.1 innings. Final Score Prediction: Arizona Diamondbacks win 5-2.