NHL Colorado Avalanche at St. Louis Blues Read more Sat 21 May, 2022, 8:00 PM (EDT) Colorado Avalanche at St. Louis Blues 5/21/22 - NHL Picks & Predictions This Saturday night May 21st, 2022 8:00pm EDT the NHL playoffs is back with more exciting hockey action. The Colorado Avalanche are in St Louis, MO to face the St Lois Blues in Enterpirse Center.