San Francisco 49ers at Los Angeles Rams 1/9/22 - NFL Picks & Predictions

By: Tony G |

Last Updated: 01/03/2022 at 10:12 PM ET

The San Francisco 49ers will face off against the Los Angeles Rams in the final week of the NFL season. This game will be available on Fox and has a kick off time of 4:25 PM Eastern. San Francisco 49ers come into this game with a record on the season of 9–7, and our winners of their last game against the Houston Texans by the score of 23–7. San Francisco has won three out of its last five games against Atlanta, Cincinnati, and Houston. The two defeats for San Francisco came against Tennessee and Seattle both on the road.

Los Angeles comes into this game with a 12–4 record on the season, and our winners of their last five consecutive games, against Baltimore, Minnesota, Seattle, Arizona, and Jacksonville. The most recent victory for the Rams came against the Baltimore ravens on the road by the score of 20 -19 on a last second effort by Cooper Kupp and Matthew Stafford.

Jimmy Garoppolo is leaving San Francisco in passing yards with 3494 to go along with 19 touchdowns and only 10 interceptions on the season. Eli Mitchell is leading the team in rushing with 878 yards and five touchdowns. Deebo Samuel is leading the team in receiving with 1310 yards on the season to go along with six touchdowns.

Matthew Stafford is leading Los Angeles in passing yards with 4648 on the season to go along with 38 touchdowns and 15 interceptions. Sony Michel is leading the team in rushing with 802 yards and four touchdowns. Cooper Kupp is leading the team in receiving with 1829 yards and 15 touchdowns on the season.

San Francisco 49ers had to start Tra Lance at quarterback last week, as Jimmy Garoppolo heals from his injury. Jimmy will most likely be back this week against Los Angeles however I do see the Rams coming away with a hard earned victory in this matchup. Final Score Prediction: Rams win 34-24.

Download the Picks and Parlays Mobile App

Get A free VIP Pick Daily!