San Francisco 49ers at LA Rams 11/29/20 - NFL Picks & Predictions

Last Updated: 11/24/2020 at 8:14 AM ET

On Sunday, the San Francisco 49ers visit SoFi Stadium in Inglewood, California for an NFC West showdown with the Los Angeles Rams. San Francisco had a bye during Week 11. The 49ers are 4-6 following a 27-13 loss to the New Orleans Saints in Week 10. The 49ers have lost each of their last three and sit in last place in the NFC West. Injuries have decimated the 49ers on both sides of the ball and the bye week could not have come at a better time.

Quarterback Nick Mullens has passed for 1,390 yards with six touchdowns, six interceptions and has been sacked 11 times. The leading active roster for San Francisco is Jerick McKinnon with 294 yards and five touchdowns and the leading active receiver is Brandon Aiyuk with 446 yards and three touchdowns. On defense, linebacker Fred Warner is the leading tackler with 79 and defensive end Kerry Hyder Jr. is the leader in quarterback sacks with 5.5.

Los Angeles improved to 7-3 following a 27-24 victory over the Tampa Bay Buccaneers on Monday Night Football. Matt Gay, who Tampa Bay had waived prior to the start of the season and was signed recently by Los Angeles, booted a field goal of 40 yards with just over two minutes to play helping give the Rams the victory. Jared Goff passed for 376 yards with three touchdowns and two interceptions and the Rams defense held Tampa Bay to 251 yards and forced two Buccaneers turnovers.

Jared Goff has passed for 2,823 yards with 16 touchdowns, eight interceptions and has been sacked 13 times. The leading rusher for Los Angeles is Darrell Henderson Jr with 491 yards and four touchdowns and the leading receiver is Cooper Kupp with 722 yards and two touchdown receptions. On defense, linebacker Micah Kiser is the leading tackler with 77 and defensive tackle Aaron Donald has a team-high 9.0 quarterback sacks.

San Francisco is coming off a bye, while Los Angeles has a shorter week having played Monday Night Football, but the Rams are playing exceptionally well off late. The Los Angeles defense held Tampa Bay to just 251 yards of total offense in their victory Monday night. Los Angeles has covered the number in four of his last six played at home. San Francisco on the other hand has failed to cover the number in four of its last five against an opponent with a winning record and has battled injuries throughout the first half of the season. Final Score Prediction, Los Angeles Rams win and cover ATS 31-21.

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