San Francisco 49ers at Atlanta Falcons 10/16/22 - NFL Picks & Predictions

Last Updated: 10/14/2022 at 7:11 PM ET

San Francisco 49ers at Atlanta Falcons 10/16/22 - NFL Picks & Predictions

The San Francisco Giants visit Mercedes-Benz Stadium in Atlanta, Georgia on Sunday to play the Atlanta Falcons. San Francisco is 3-2 following its 37-15 victory over the Carolina Panthers on Sunday. Jimmy Garoppolo passed for 253 yards and two touchdowns, while Jeff Wilson Jr. rushed for 120 yards and one touchdown. San Francisco gained 397 yards of total offense and held Carolina to 308 yards of total offense.

San Francisco quarterback Jimmy Garoppolo has thrown for 857 yards with five touchdowns and one interception. The leading rusher is Jeff Wilson Jr. with 375 yards and two touchdowns, while the leading receiver is Deebo Samuel with 266 yards and two touchdown receptions. On defense, linebacker Dre Greenlaw is the leading tackler with 49. San Francisco has 21 quarterback sacks and five interceptions.

Atlanta dropped to 2-3 following its 21-15 loss to the Tampa Bay Buccaneers on Sunday. Atlanta was held to just 261 yards of total offense and the Falcons allowed 420 yards of total offense to Tampa Bay. Atlanta quarterback Marcus Mariota passed for 147 yards and one touchdown. Atlanta was called for a roughing-the-passer penalty, which was disputed by Falcons’ players and coaches, and took place on 3rd down in the final three minutes of the game giving Tampa Bay an additional first down.

Quarterback Marcus Mariota has thrown for 926 yards with four touchdowns and four interceptions. The leading rusher is Cordarrelle Patterson with 340 yards and three touchdowns and the leading receiver is Drake London with 266 yards and two touchdown receptions. On defense, linebacker Mykal Walker is the leading tackler with 44. Atlanta has eight quarterback sacks and four interceptions.

San Francisco is coming off a victory over Carolina in which the 49ers defense came up big and will do so again against the Atlanta Falcons on Sunday. San Francisco has covered the number in eight of its last 10. Jimmy Garoppolo has taken the reins once again following a season-ending injury to Trey Lance and the 49ers’ quarterback has guided the club to three wins in the last four games. Final Score Prediction, San Francisco 49ers win and cover ATS 27-17.

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