New England Patriots at Buffalo Bills 12/6/21 - NFL Picks & Predictions

Last Updated: 12/06/2021 at 9:43 PM ET

An AFC East Division showdown will take place on Monday night, when the New England Patriots visit the Buffalo Bills. The Patriots (8-4) are riding a six-game winning streak and rank first in the league in scoring defense (15.8 ppg). On Sunday, New England forced four turnovers en route to a 36-13 home victory versus Tennessee. 

Rookie QB Mac Jones shredded the Tennessee secondary for 310 yards and two touchdowns. New England RB Damien Harris added a 14-yard touchdown run to cap the scoring.

The Buffalo Bills lead the league in total defense and trail the Patriots by a half-game for the division lead. On Thanksgiving night, Buffalo shut out New Orleans through the first three quarters of a 31-6 road triumph. The Bills (7-4) outgained the Saints by a 361-190 margin and possessed the ball for nearly 35 minutes.

Buffalo QB Josh Allen threw for 260 yards and four touchdowns, including two first-half strikes to TE Dawson Knox. WR Stefon Diggs caught seven passes for 73 yards and found the end zone from five yards out. 

Buffalo CB Tre’Davious White suffered a torn ACL during Thursday’s victory and will miss the rest of the season. The Patriots have been the best team in the league over the last month and should be able to keep things close. Take the under in a matchup of terrific defenses. Final Score Prediction, Buffalo Bills win 20-17.

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