Kansas City Chiefs at Indianapolis Colts 9/25/22 - NFL Picks & Predictions

In the NFL week 3, the Kansas City Chiefs will travel on the road to face off against the Indianapolis Colts at Lucas Oil Stadium on Sunday for a scheduled kickoff time of 1:00 PM eastern. This game will be available on CBS. Kansas City comes into this game with a record on the year of two wins, zero losses being victorious by the score of 27-24 over the Los Angeles chargers, and was victorious on the road against the Arizona Cardinals by the score of 44-21. 

The Indianapolis Colts come into this game with a record on the season of zero wins, one loss, and one tie coming on the road against the Houston Texans after a scoreless overtime. The one loss came against the Jacksonville Jaguars on the road by the score of 24-0. 

Patrick Mahomes is the team leader for Kansas City and passing with 595 yards on the season to go along with seven touchdowns and zero interceptions. Clyde Edwards Helaire is the team leader in rushing with 116 yards on the season.

Matt Ryan is the team leader for the Indianapolis Colts in passing going 48-80 on the season for 547 yards and only one touchdown and four interceptions. Jonathan Taylor is the team leader for the Indianapolis Colts in rushing with 215 yards on the season and one touchdown on 40 carries.