• Home
  • /
  • Sports Articles
  • /
  • Kansas City Chiefs at Arizona Cardinals 8/20/21 - NFL Preseason Picks & Predictions

Kansas City Chiefs at Arizona Cardinals 8/20/21 - NFL Preseason Picks & Predictions

Game: Arizona Cardinals vs Kansas City Chiefs
Date & Time: 8/21/2021, 12:00 AM UTC
Location: State Farm Stadium,
Address: Glendale, USA
Latest Odds: KC -2.5 ; O/U 41
TV Channel: ESPN

The Kansas City Chiefs visit the Arizona Cardinals in week 2 of the NFL preseason on Friday. Kansas City opened its preseason with a 19-16 victory over the San Francisco 49ers. Kansas City played all but one of its 22 starters with the exception being linebacker Willie Gay who did not see any action. Chiefs Linebacker Darius Harris hurt his hand and did not return.

Kansas City star quarterback Patrick Mahomes has played only one series but is expected to see more action on Friday against Arizona. Mahomes played behind a completely overhauled offensive line that has five new starters of which three have never played in an NFL regular season game. Mahomes completed one pass in his four plays and threw an incompletion on third down. Chiefs backup quarterback Anthony Gordon passed for 79 yards and helped to rally the Chiefs from a first half deficit to the win.

Arizona opened its preseason last Friday with a 19-16 victory over the Dallas Cowboys. Rookie linebacker Zaven Collins played well in the middle and Matt Prater kicked one field goal to tie the game and a second to win it for the Cardinals. Cardinals starter quarterback Kyler Murray did not play. Eno Benjamin scored a 6-yard touchdown for the Cardinals. Colt McCoy, who started at quarterback for Arizona, passed for 69 yards.

Chris Streveler took over for Colt McCoy and completed 12 of 24 passes for 107 yards and Streveler and McCoy will once again see most of the action on Friday against Kansas City although Kyler Murray is expected to play. Cardinals running back Jonathan Ward injured his ankle in the third quarter, while safety Chris Banjo left the game with a hamstring injury. 

Odds Table

Betting Trends

  • Kansas City is 2-9-1 ATS in its last 12
  • The UNDER has cashed in 4 of the Chiefs last 6
  • Arizona is 3-7 ATS in its last 10
  • The UNDER has cashed in 4 of the Cardinals last 5
No house advantage
Bet on player over/unders to win 21x your bet at No House Advantage.
Click here to get a 1st deposit match up to $50 w/ promocode PandP!
Free NFL Pick: Arizona Cardinals +2.5

Kansas City will once again play its starters but in a very limited role, while Arizona is expected to have its starting players see much more action including quarterback Kyler Murray and his leading wide receiver DeAndre Hopkins. In the opening game of the pre-season, Arizona rushed for 168 yards and look for much of the same against a Kansas City defense that is not known for its strength against the run. Final Score Prediction, Arizona Cardinals win and cover ATS 24-20.


Terry Edelmann
WIN/LOSS 71/63
PROFIT $1084.00
Stephen Nover
WIN/LOSS 63/48
PROFIT $1050.00
Mike Lundin
WIN/LOSS 54/40
PROFIT $873.00
Jesse Schule
WIN/LOSS 51/37
PROFIT $845.00
Tony Karpinski
WIN/LOSS 52/43
PROFIT $493.00

Free Picks & Predictions