Jacksonville Jaguars at Los Angeles Chargers 9/25/22 - NFL Picks & Predictions

Last Updated: 09/19/2022 at 6:46 PM ET

Jacksonville Jaguars at Los Angeles Chargers 9/25/22 - NFL Picks & Predictions

The Jacksonville Jaguars visit SoFi Stadium in Inglewood, California on Sunday to play the Los Angeles Chargers. Jacksonville is 1-1 following its 24-0 victory over the Indianapolis Colts on Sunday. Jacksonville's defense stepped up, holding Indianapolis to 218 yards of total offense and forcing the Colts into three turnovers. Jacksonville gained 331 yards of total offense. Christian Kirk caught a pair of touchdown passes for the Jaguars. Look for more free NFL predictions.

Jacksonville quarterback Trevor Lawrence has passed for 510 yards with three touchdowns and one interception. The leading rusher is James Robinson with 130 yards and two touchdowns, while leading receiver is Christian Kirk with 195 yards and two touchdown receptions. On defense, linebacker Devin Lloyd is the leading tackler with 17. Jacksonville has six quarterback sacks and five interceptions.

Los Angeles dropped to 1-1 following its 27-24 loss on Thursday night to the Kansas City Chiefs. Los Angeles gained 401 yards of total offense and held Kansas City to 319 yards of total offense, but a 99-yard pick-six for Kansas City was the difference, preventing Los Angeles from an almost sure TD and giving Kansas City seven points, early in the fourth quarter.

Los Angeles quarterback Justin Hebert has passed for 613 yards with six touchdowns and one interception. The leading rusher is Austin Ekeler with 75 yards while the leading receiver is Gerald Everett with 125 yards and one touchdown. Mike Williams has 123 yards receiving and one touchdown. On defense, safety Derwin James Jr is the leading tackler with 15. Los Angeles has seven quarterback sacks and three interceptions.

Los Angeles will pick up a victory at home on Sunday against Jacksonville, but the Jaguars defense will play well enough to keep the score close and cover. Los Angeles quarterback Justin Hebert is questionable with possible damage to rib cartilage and that could affect the signal caller’s passing. Jacksonville's defense came up big last week when shutting out Indianapolis and holding Matt Ryan and the Colts to just 218 yards of total offense. Final Score Prediction, Los Angeles Chargers win but fall short ATS 24-20.

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