Jaguars vs Colts Picks and Prediction – 1/5/2025

By: David Anicetti |

Last Updated: 12/30/2024 at 8:43 PM ET

Jacksonville Jaguars at Indianapolis Colts 01/05/25 - NFL Picks & Predictions
Game Start: 1/5/2025, 6:00 PM UTC
Latest Odds: IND -5.5 ; O/U 45

Jaguars vs Colts Prediction

The Jacksonville Jaguars visit Lucas Oil Stadium in Indianapolis on Sunday to play the Indianapolis Colts in a game between two teams that have no chance of reaching the postseason. Jacksonville is 4-12 and defeated the Tennessee Titans 20-13 on Sunday, snapping a two-game losing streak for the Jaguars. Jacksonville gained 295 yards of total offense led by quarterback Mac Jones with 174 yards passing and two touchdowns. Keep up to date with all the NFL action, with our NFL picks.

Jacksonville backup quarterback Mac Jones has thrown for 1,447 yards with seven touchdowns and seven interceptions. Jones has been sacked 12 times in nine games. Tank Bigsby leads all rushers for Jacksonville with 727 yards and six touchdowns. Brian Thomas Jr is the leading receiver with 1,179 yards and 10 touchdown receptions. Jacksonville's defense has made 31 quarterback sacks and intercepted six passes.

The Indianapolis Colts are 7-9, which is a second in the AFC South but were eliminated from playoff contention when losing to the New York Giants 45-33 Sunday. Indianapolis gained 446 yards of total offense but the Colts committed three costly turnovers and allowed New York to gain 389 yards. Indianapolis backup quarterback Joe Flacco passed for 330 yards with two touchdowns and two interceptions.

Indianapolis quarterback Joe Flacco has thrown for 1,497 yards with 11 touchdowns and 7 interceptions. Flacco has been sacked 15 times and seven games. Jonathan Taylor is the leading rusher with 1,254 yards and 10 touchdowns. Alec Pierce is the leading receiver with 767 yards and six touchdown receptions. The Indianapolis defense has made 34 quarterback sacks and intercepted 15 passes.

Jaguars vs Colts Pick Analysis

With nothing on the line for these two teams, the difference will be Indianapolis playing at home and the Colts digging deeper to pick up a victory. Indianapolis has a strong running attack led by Jonathan Taylor with 1,254 yards and will face a Jacksonville defense that is 21st against the run. Final Score Prediction, Indianapolis Colts win and cover ATS 31-17.

Our Free NFL Pick for Indianapolis Colts vs Jacksonville Jaguars