Jacksonville Jaguars at Indianapolis Colts 10/16/22 - NFL Picks & Predictions

On Sunday, the Jacksonville Jaguars visit Lucas Oil Stadium in Indianapolis, Indiana to play the Indianapolis Colts. Jacksonville dropped to 2-3 following its 13-6 loss to the Houston Texans on Sunday. Jacksonville gained 422 yards of total offense but committed two costly turnovers and played poorly in the red zone. Quarterback Trevor Lawrence passed for 286 yards but was intercepted twice.

Jacksonville quarterback Trevor Lawrence has thrown for 1,232 yards with eight touchdowns and four interceptions. The leading rusher is James Robinson with 286 yards and three touchdowns while the leading receiver is Christian Kirk with 338 yards and three touchdown receptions. On defense, linebacker Devin Lloyd is the leading tackler with 49. Jacksonville has 10 quarterback sacks and seven interceptions.

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Indianapolis improved to 2-2-1 following its 12-9 victory over the Denver Broncos on Thursday Night Football. Indianapolis gained only 306 yards of total offense and committed two turnovers, while the Colts held Denver to 375 yards of total offense and forced the Broncos into two costly turnovers. Chase McLaughlin kicked four field goals in the victory for Indianapolis in a game in which no touchdowns were scored.

Indianapolis quarterback Matt Ryan has thrown for 1,376 yards with five touchdowns and seven interceptions. Jonathan Taylor is the leading rusher with 328 yards and one touchdown, while the leading receiver is Michael Pittman Jr. with 283 yards and one touchdown reception. On defense, linebacker Zaire Franklin is the leading tackler with 54. Indianapolis has 11 quarterback sacks and three interceptions.