Jaguars vs Bills Picks and Prediction – 9/23/2024

Highmark Stadium will play host to a Monday night NFL clash between the Jacksonville Jaguars and the Buffalo Bills. Get ready for all the football action with our NFL Picks. The Jaguars (0-2) are off to a disappointing start and are averaging just 15 points per contest. On Sunday, Jacksonville trailed by ten points at halftime and was unable to take advantage of 13 Cleveland penalties during an 18-13 home loss. 

Jacksonville trimmed the Cleveland lead to 16-10 late in the third quarter on a four-yard Travis Etienne touchdown run. Trevor Lawrence was an inefficient 14-for-30 passing for 220 yards and Brian Thomas Jr. added a game-high 94 receiving yards for the Jaguars. 

The Buffalo Bills are the only undefeated team in the AFC East Division and have scored 30 plus points in their two victories. On Thursday, Buffalo built a ten-point halftime lead and coasted to a 31-10 road triumph against Miami. The Bills (2-0) took advantage of three turnovers and averaged 5.5 yards per play. 

Buffalo RB James Cook found the end zone on a 17-yard touchdown reception and added two scores on the ground. Cook finished with a game-high 78 rushing yards on just 11 carries. Josh Allen threw for 139 yards and Khalil Skakir contributed five receptions for 54 yards. 

Jacksonville TE Evan Engram suffered a hamstring injury during Sunday’s pregame warmups and is listed as week-to-week. This will be an interesting battle featuring two of the best quarterbacks in the league. The Jaguars need a win in the worst way and are the side to back. Final Score Prediction, Buffalo Bills win 24-23.