Indianapolis Colts at Jacksonville Jaguars 9/18/22 - NFL Picks & Predictions

On Sunday, the Indianapolis Colts visit TIAA Bank Field in Jacksonville, Florida to play the Jacksonville Jaguars. Indianapolis opened its season with a 20-20 tie against the Houston Texans. Indianapolis gained 517 yards of total offense but turned the ball over twice. The Indianapolis defense gave up just 299 yards of total offense to Houston. Indianapolis rallied with 14 points in the fourth quarter after trailing 20-6 through three quarters.

Indianapolis quarterback Matt Ryan has passed for 352 yards with one touchdown and one interception. The leading rusher is Jonathan Taylor with 161 yards and one touchdown. Michael Pittman Jr. is the leading receiver with 121 yards and one touchdown. On defense, Zaire Franklin is the leading tackler with eight, while the leader in quarterback sacks is Kwity Paye with 2.0. Indianapolis does not have an interception through one game. Make sure you get the best NFL picks with our free football previews.

Jacksonville opened its regular season with a 28-22 loss on the road to the Washington Commanders. Jacksonville held a 22-14 lead during the fourth quarter but gave up two Washington touchdowns over the final nine minutes to lose by six. Jacksonville gave up 390 yards of total offense to Washington and the Jaguars gained 383 yards of total offense.

Trevor Lawrence has passed for 275 yards with one touchdown and one interception. The leading rusher is James Robinson with 66 yards and one touchdown while the leading receiver is Christian Kirk with 117 yards. On defense, Devin Lloyd is the leading tackler with 11, while Foyesdale Oluokun has 10. The leader in quarterback sacks is Travon Walker with 1.0, while Tyson Campbell and Walker each have one interception.