Lions vs Colts Picks and Prediction – 11/24/2024

By: David Anicetti |

Last Updated: 11/18/2024 at 9:34 PM ET

Detroit Lions at Indianapolis Colts 11/24/24 - NFL Picks & Predictions
Game Start: 11/24/2024, 6:00 PM UTC
Latest Odds: DET -8 ; O/U 50.5

Lions vs Colts Prediction

The Detroit Lions visit Lucas Oil Stadium in Indianapolis on Sunday to play the Indianapolis Colts. Detroit is 9-1 and first in the NFC North, one game ahead of the Minnesota Vikings. Detroit defeated the Jacksonville Jaguars 52-6 on Sunday for their 8th consecutive win. Detroit gained 645 yards of total offense and held Jacksonville to just 170 yards of total offense. Keep up to date with all the NFL action, with our expert NFL picks.

Detroit quarterback Jared Goff has thrown for 2,492 yards with 20 touchdowns and nine interceptions. Jahmyr Gibbs is leading Detroit in rushing with 796 yards and an average of 6.0 yards per carry. Gibbs has scored eight touchdowns. Amon-Ra St. Brown is the leading receiver for Detroit with 685 yards and an average of 10.5 yards per reception. Detroit's defense has 25 quarterback sacks and 14 interceptions.

The Indianapolis Colts look for their second consecutive victory when hosting Detroit on Sunday. Indianapolis is 5-6 and second in the AFC South, 1 ½ games behind the first-place Houston Texans. Indianapolis defeated the New York Jets 28-27 on Sunday to snap a three-game losing skid. Indianapolis scored with just 46 seconds left to play for the one-point victory. 

Indianapolis starting quarterback Anthony Richardson has thrown for 1,230 yards with five touchdowns and seven interceptions. Jonathan Taylor leads all rushers for Indianapolis with 673 yards and five touchdowns. Alec Pierce is the leading receiver with 590 yards and four touchdown receptions. The Indianapolis defense has made 25 quarterback sacks and intercepted eight passes.

Lions vs Colts Pick Analysis

Detroit will be too much for Indianapolis on Sunday as the Lions will use their explosive offense to build a double-digit lead and win. Detroit has covered the number in seven of its last eight. Detroit is first in the NFL in scoring with an average of 33.6 points per game and has the fifth-best defense in points allowed at just 17.7 points per game. Indianapolis is scoring an average of only 21.5 points per game and allows slightly more at 22.7 points per game. Final Score Prediction, Detroit Lions win and cover ATS 34-20.

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