Bears vs Colts Picks and Prediction – 9/22/2024

By: David Anicetti |

Last Updated: 09/16/2024 at 7:31 PM ET

Chicago Bears at Indianapolis Colts 09/22/24 - NFL Picks & Predictions
Game Start: 9/22/2024, 5:00 PM UTC
Latest Odds: IND -1 ; O/U 44.5

Bears vs Colts Prediction

The Chicago Bears visit Lucas Oil Stadium in Indianapolis on Sunday to play the Indianapolis Colts. Chicago dropped to 1-1 following its 19-13 loss to the Houston Texans on Sunday Night Football. Chicago struggled as the Bears gained just 205 yards of total and committed a pair of turnovers. Chicago was able to hold Houston to 310 yards of total offense but could not overcome their problems while in possession. Keep up to date with all the NFL action, with our expert NFL picks.

Chicago quarterback Caleb Williams has passed for just 267 yards with two interceptions. Williams has been sacked nine times. Williams is the leading rusher with 59 yards and D’Andre Swift has rushed for 48 yards. The leading receiver is DJ Moore with 89 yards. Linebacker TJ Edwards is the leading tackler with 23. Chicago's defense has made six quarterback sacks and intercepted two passes.

The Indianapolis Colts dropped to 0-2 following a 16-10 loss on the road to the Green Bay Packers on Sunday. Indianapolis gained 338 yards of total offense and allowed 383 yards of offense to Green Bay. The big difference was turnovers as Indianapolis committed three and Green Bay committed just one. Indianapolis quarterback Anthony Richardson had one touchdown pass but threw three interceptions.

Indianapolis quarterback Anthony Richardson passed for 416 yards with three touchdowns and four interceptions, while being sacked three times. Jonathan Taylor is the leading rusher with 151 yards and one touchdown. Alec Pierce is the leading receiver with 181 yards and two touchdown receptions. Safety Nick Cross is the leading tackler with 29. The Indianapolis defense has made four quarterback sacks and intercepted two passes. 

Bears vs Colts Pick Analysis

Chicago rookie quarterback Caleb Williams had a tough time in his first two games but will bounce back on Sunday with a strong effort on the road against Indianapolis. However, the play here is UNDER as both struggled to score last time out, as Chicago scored just 13 and Indianapolis just 10. The UNDER has cashed in six of Chicago’s last eight and three of Indy’s last five. Final Score Prediction, Chicago Bears win but our best play is UNDER 21-20.

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