Buffalo Bills at Tennessee Titans 10/18/21 - NFL Picks & Predictions

Nissan Stadium will play host to a Monday night NFL football clash between the Buffalo Bills and the Tennessee Titans. The Bills (4-1) own the top defense in the league and look like the best team in the AFC Conference. On Sunday night, Buffalo built an 11-point halftime lead and forced four turnovers during a 38-20 road triumph against Kansas City.

Buffalo QB Josh Allen continued his stellar play with 315 yards passing and three touchdowns. TE Dawson Knox reeled in three passes for 117 yards and found the end zone on a 53-yard reception.

The Tennessee Titans currently sit atop the AFC South Division standings and rank 11th in the league in total offense (389.2 ypg). On Sunday, Tennessee played without WR Julio Jones during an easy 37-19 home victory versus Jacksonville. The Titans (3-2) averaged 5.1 yards per rushing attempt and forced two turnovers on the afternoon.

Kevin Byard put Tennessee on the scoreboard one minute into the game with a 30-yard fumble return for a touchdown. Derrick Henry carried 29 times for 130 yards and three touchdowns for the Titans.