Bills vs Patriots Picks and Prediction – 1/5/2025

As the NFL regular season draws to a close, the Buffalo Bills (13-3) are set to face the New England Patriots (3-13) on January 5, 2025, at Gillette Stadium in Foxborough. Kickoff is scheduled for 1:00 PM ET (10:00 AM PT), with the game broadcast on CBS. Get in on the action with our free NFL picks.

The Bills, having clinched the AFC East title for the fifth consecutive year, are riding high into the new year. Their recent victory over the Detroit Lions showcased their offensive prowess, with quarterback Josh Allen leading the charge. Allen, a frontrunner for the NFL MVP award, has been instrumental in Buffalo's success this season. With the No. 2 seed in the AFC playoffs secured, there is speculation that the Bills may rest key starters to preserve their health for the postseason. We should see Mitch Trubisky at QB in Allen's absence.

In contrast, the Patriots have endured a challenging season, currently holding a 3-13 record. Their recent performances have been marred by a six-game losing streak, and they are vying for the first overall pick in the 2025 NFL Draft. Despite these struggles, the Patriots have a history of resilience, especially at home. However, with key players sidelined due to injuries and suspensions, the team faces an uphill battle against a formidable Bills squad. Drake Maye has shown glimpses of brilliance, giving fans reason for optimism.

The final week of the NFL season is the worst to bet on, and this game is a prime example. We will likely see backups with little motivation squaring off. We need some action though and the value here is on the Patriots. Buffalo has nothing to play for, and New England would like to get a win on them in front of their home fans before the offseason. Prediction: Patriots win 17-14.