Bills vs Chiefs Picks and Prediction – 1/26/2025

By: David Anicetti |

Last Updated: 01/20/2025 at 7:36 PM ET

Buffalo Bills at Kansas City Chiefs 01/26/25 - NFL Picks & Predictions
Game Start: 1/26/2025, 11:30 PM UTC
Latest Odds: KC -2 ; O/U 48.5

Bills vs Chiefs Prediction

On Sunday, the Buffalo Bills visit GEHA Field at Arrowhead Stadium in Kansas City to play the Kansas City Chiefs in the AFC Championship Game. Buffalo defeated the Baltimore Ravens 27-25 on Sunday night in an AFC divisional game and the week before defeated the Denver Broncos 31-7 in the wildcard round. Dating back to the regular season, Buffalo has won five of the last six, with only a loss to New England in a game with no playoff implications. Keep up to date with all the NFL action, with our expert NFL picks.

In two playoff games, Buffalo quarterback Josh Allen has thrown for 399 yards with a pair of touchdowns and no interceptions. James Cook has rushed for 187 yards with one touchdown, averaging 4.7 yards per carry. Khalil Shakir has 128 yards receiving to lead Buffalo with an average of 10.7 yards per reception, but no touchdown receptions in the postseason. Buffalo's defense has four quarterback sacks and one interception in the playoffs.

The Kansas City Chiefs look to move on to Super Bowl LIX with a victory at home on Sunday when hosting Buffalo in the AFC Championship game. Kansas City had a bye in the wildcard round and defeated the Houston Texans 23-14 on Saturday in the AFC divisional round. Dating back to the regular season, Kansas City has won six of the last seven, with only a loss to Denver in a game with no playoff implications. 

In one playoff game, Kansas City quarterback Patrick Mahomes has thrown for 177 yards with one touchdown. Mahomes was sacked three times in the win over Houston. Kareem Hunt has 44 yards rushing and one touchdown for Kansas City in the playoffs. Travis Kelce has 117 yards receiving with one touchdown reception. Kansas City's defense made eight quarterback sacks versus Houston but did not intercept any passes.

Bills vs Chiefs Pick Analysis

The Kansas City Chiefs will avenge a loss during the regular season to Buffalo with a victory on Sunday versus the Bills and move on to Super Bowl LIX. Kansas City held Houston to 14 points in its AFC divisional round victory and would have covered the number if not for taking a safety in the final seconds after leading by 11 points and winning by nine. Kansas City was defeated by Buffalo 30-21 in Week 11 but is 7-1 straight up since. Final Score Prediction, Kansas City Chiefs win and cover ATS 28-24.

Our Free NFL Pick for Kansas City Chiefs vs Buffalo Bills