Bills vs Colts Picks and Prediction – 11/10/2024

The Buffalo Bills visit Lucas Oil Stadium in Indianapolis on Sunday to play the Indianapolis Colts. Buffalo improved to 7-2 following a 30-27 victory over the Miami Dolphins on Sunday. Buffalo is first in the AFC East, four games ahead of the New York Jets. Buffalo’s Tyler Bass kicked a 61-yard field goal with just 5 seconds remaining to give the Bills the win at home. Keep up to date with all the NFL action, with our NFL predictions.

Buffalo quarterback Josh Allen has thrown for 2,001 yards with 17 touchdowns and only two interceptions. Allen has been sacked 11 times in nine games. James Cook leads all rushers for Buffalo with 496 yards and seven touchdowns. Khalil Shakir is the leading receiver with 471 yards and two touchdown receptions. The Buffalo defense has made 21 quarterback sacks and intercepted eight passes.

The Indianapolis Colts look to snap a two-game losing skid with a victory at home on Sunday when hosting Buffalo. Indianapolis is 4-5 and second in the AFC South after losing to the Minnesota Vikings 21-13 on Sunday Night Football. Indianapolis was held to only 227 yards of total offense and committed two costly turnovers. Quarterback Joe Flacco passed for 179 yards and one interception.

Indianapolis starting quarterback Joe Flacco has thrown for 895 yards with seven touchdowns and two interceptions. The veteran signal-caller has been sacked nine times in five games. Jonathan Taylor leads all rushers for Indianapolis with 502 yards and five touchdowns. Alec Pierce is the leading receiver with 435 yards and three touchdown receptions. The Indianapolis defense has made 20 quarterback sacks and intercepted six passes.

Buffalo will pick up another victory on the road Sunday when visiting Indianapolis but the play here is UNDER. The UNDER has cashed in five of Buffalo's last six played on the road, four of Indianapolis' last five overall, and seven of the last 10 played head-to-head between Buffalo and Indianapolis. Buffalo is allowing an average of only 19.2 points per game and Indianapolis allows just 21.4 points per game. Final Score Prediction, Buffalo Bills win but our best play is UNDER 24-20.