Bills at Bears 8/21/21 - NFL Preseason Picks & Predictions

Game: Chicago Bears vs Buffalo Bills
Date & Time: 8/21/2021, 5:00 PM UTC
Location: Soldier Field,
Address: Chicago, IL
Latest Odds: CHI -4.5 ; O/U 38.5
TV Channel: NFL

The Buffalo Bills visit Soldier Field on Saturday to play the Chicago Bears in a week 2 NFL preseason matchup. Buffalo opened its preseason with a 16-15 victory over the Detroit Lions last Friday. Quarterback Jake Fromm led a scoring drive of 74 yards that resulted in a Tyler Bass game-winning field goal. Fromm passed for 65 yards including a 42-yard reception on fourth down in the final drive of the game.

Buffalo held out several of its starters and is expected to do the same on Saturday against the Bears. Andre Smith had eight tackles to lead Buffalo on defense while Mike Bell and Damar Hamlin each had a quarterback sack for the Bills defense. Wide receiver Stefon Diggs has been listed as questionable due to a knee injury and will likely not see action on Saturday versus Chicago. Star Quarterback Jake Allen did not play on Friday versus the Lions and is likely to sit out until the final preseason game.

Chicago opened its preseason schedule with a 20-13 victory over the Miami Dolphins. The Bears put up 339 total yards while allowing 326. Rookie quarterback Justin Fields completed passes for 142 yards and one touchdown while veteran Nick Foles and Andy Dalton saw limited playing time. Artavis Pierce was the leading rusher for Chicago with 50 yards.

On the defensive side of the ball, Chicago was led by Duke Shelley with six tackles, while Daniel Archibong collected a quarterback sack and DeAndre Houston-Carson picked off a Miami pass. Chicago has added former Philadelphia offensive lineman Jason Peters, who is expected to compete for the starting left tackle position. Rookie Teven Jenkins was originally expected to play in that position but has been sidelined with a back injury since the start of training camp.

Odds Table

Betting Trends

  • Buffalo is 9-2 ATS in its last 11
  • The OVER has cashed in 4-1 of the Bills last 5 on the road
  • Chicago is 2-5 ATS in its last 7 on grass
  • The OVER has cashed in 5 of the Bears last 7
No house advantage
Bet on player over/unders to win 21x your bet at No House Advantage.
Click here to get a 1st deposit match up to $50 w/ promocode PandP!
Free NFL Pick: Chicago Bears -4.5

Buffalo will have several of its top players out on Saturday including wide receiver Stefon Diggs who is nursing a knee injury. Bills quarterback Jake Allen is not expected to play, while Chicago has a quarterback battle between veterans Andy Dalton and Nick Foles along with top draft pick Justin Fields, which could create much more scoring against a Bills defense that will have both starters and second string players on the field. Final Score Prediction, Chicago Bears win and cover ATS 24-18.


Scott Rickenbach
WIN/LOSS 84/56
PROFIT $2343.00
Terry Edelmann
WIN/LOSS 73/63
PROFIT $1336.00
Will Rogers
WIN/LOSS 62/44
PROFIT $1308.00
Mike Lundin
WIN/LOSS 54/37
PROFIT $1230.00
Cameron Ross
WIN/LOSS 44/29
PROFIT $1147.00

Free Picks & Predictions