Cardinals vs Bills Picks and Prediction – 9/8/2024

The Arizona Cardinals open the 2024 season with a tall task on the road in Buffalo against the Bills. The Cardinals were one of the worst teams in football a year ago finishing the season with just four wins in 13 games played including a 1-8 start overall. Quarterback Kyler Murray returned from injury just past the midway point of the season and played eight games total for Arizona a year ago. Murray was able to complete 176 passes for 1799 yards and 10 scores across eight games last season. For other NFL news see our NFL Picks.

Kyler Murray is expected to start the season for Arizona at quarterback as he seemingly has returned to 100% since the knee injury. Offensively Arizona is expected to be better with their star quarterback back on the field The Cardinals have added more depth and talent to their offense giving Kyler Murray more weapons to spread the ball to. Arizona has a strong running back in James Connor to carry the brunt of the load early on but several new faces will help make an improvement. Defensively Arizona made moves signing multiple free agents to boast one of the weakest defenses in the league that should see a complete turnaround in 2024.

The Buffalo Bills come into the 2024 season following an 11 win 2023 that sawtheir season come to a close once again against the Kansas City Chiefs. Buffalo has been a perennial powerhouse in the AFC over the last few years but will have a new look in some cases this season. Buffalo will still feature MVP candidate Josh Allen at quarterback, but Allen will be without his top two receivers from the past few years. In 2024 free agent Curtis Samuel will be featured heavily in the Buffalo offense as well as a few other new pieces to the team.

Buffalo has been a top 10 defense over the last few years and will likely have to get better this season due to the loss of offensive weapons. Buffalo was the depleted in the offseason losing several key pieces and will lean heavily on their returners from a year ago. Buffalo will have several new faces that will bolster the roster but the pressure from the defensive line could make or break that side of the ball.

Both teams are expected to have success this season, but Buffalo is the better team. The Bills window for a Super Bowl is closing if it hasn't already. Look for Buffalo to start the 2024 year on the right foot as they overwhelm one of the worst teams in the league from a year ago. Take Buffalo to start the season strong as they get the home win and cover in week one. Final Score Prediction, Buffalo Bills win and cover 27-10.