St. Louis Cardinals at Boston Red Sox 6/17/22 - MLB Picks & Predictions

Last Updated: 06/16/2022 at 10:59 PM ET

The St. Louis Cardinals open a three-game interleague series on the road Friday at Fenway Park with the Boston Red Sox. St. Louis dropped to 37-28 following its 6-4 loss to the Pittsburgh Pirates on Wednesday. The loss snapped a three-game winning streak for the Cardinals. St. Louis is first in the National League Central, 1 ½ games ahead of the second place Milwaukee Brewers.

First baseman Paul Goldschmidt is batting .347 with 16 home runs, 56 RBIs, 82 hits and an on-base percentage of .430 to lead St. Louis in each of the six categories. Third baseman Nolan Arenado has 11 home runs and 41 RBIs which are second to Goldschmidt in both. On Friday, the St Louis Cardinals will send Adam Wainwright to the mound. The right-hander is 5-4 with a 2.84 ERA, 55 Ks and 23 BBs.

Boston improved to 34-20 following its 10-1 rout of the Oakland Athletics on Wednesday. Rafael Devers hit a home run for the fourth consecutive game and Alex Verdugo homered for the first time in close to two months. The Red Sox have won three straight and 11 of the last 13. Boston is fourth in the American League East, 12 ½ games behind the first-place New York Yankees.

J.D. Martinez is batting .345 to lead Boston and the designated hitter has a team-high .417 on-base percentage. Third baseman Rafael Devers is the leader in home runs with 16 and hits with 85, while second baseman Trevor Story is the leader in RBIs with 42. On Friday, the Boston Red Sox will send Michael Wacha to the mound. The right-hander is 4-1 with a 2.33 ERA, 36 Ks and 16 BBs.

Boston has dominated its matchup with St Louis, winning each of the last four overall and five of the last six played at home in Fenway Park against the Cardinals. Boston right-hander Michael Wacha has pitched well in two out of the last three outings allowing a combined three earned runs on 14 hits across 19 innings. St Louis has struggled in interleague play, losing each of its last four. Final Score Prediction, Boston Red Sox win 5-3.

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