Giants vs Astros Picks and Prediction – 4/2/2025

The Houston Astros remain at home on Wednesday with the San Francisco Giants in town. Houston is averaging 2 runs scored per game with 4.5 hits. The Astros won their first series of the season beating the Mets 2-1 in a three game series. Houston allowed 7 runs when they lost to the Giants on Monday. Stay up to date with our expert's MLB Picks. 

Framber Valdez will make his 2nd start on the mound for the Houston Astros. Valdez is 1-0 on the season with 7 innings pitched. Valdez has 4 strikeouts and didn't allow any earned runs in his debut. Valdez went 15-7 last season and posted a 2.91 ERA. 

The San Francisco Giants beat the Red in their opening series. The Giants are averaging 5.3 runs scored per game with 7.5 hits. San Francisco had 9 hits and 7 runs on Monday when they beat the Astros. The Giants have 6 home runs on the season. 

Landen Roupp will make the start on the mound for the Giants. Roupp went 1-2 last season with 50.1 innings pitched. Roupp had 47 strikeouts and posted a 3.58 ERA. The San Francisco Giants carry a 3.09 team ERA. 

The San Francisco Giants entered the week playing better baseball than the Astros. Houston is a favorite on Wednesday as they have home field advantage and feature Framber Valdez on the mound. Valdez looked solid in his debut. The value is in the total. Final Score Prediction, San Francisco Giants win, but the play is on the UNDER 3-1.