San Diego Padres at Seattle Mariners 9/14/22 - MLB Picks & Predictions

Last Updated: 09/13/2022 at 10:53 PM ET

The San Diego Padres complete a two-game interleague series on the road Wednesday against the Seattle Mariners. San Diego is 77-64 following its 11-2 loss to the Los Angeles Dodgers on Sunday. San Diego lost two of three to LA and the Padres are second in the National League West 20 ½ games behind first place. San Diego is currently holding the third and final NL wild-card spot, two games ahead of Milwaukee.

Third baseman Manny Machado is batting .301 with 28 home runs, 90 RBIs, 151 hits and an on-base percentage .369 to lead San Diego in each category. Trent Grisham is second in home runs with 17 and Jake Cronenworth is second in RBIs with 73. On Wednesday, the San Diego Padres will send Mike Clevinger to the mound. The right-hander is 5-6 with a 4.13 ERA, 81 Ks and 30 BBs.

Seattle improved to 79-61 following its 8-7 victory over the Atlanta Braves on Sunday. Eugenio Suarez and Julio Rodriguez each hit two home runs for the Mariners. Seattle is second in the American League West, 11 ½ games behind first place and the Mariners are currently tied with the Toronto Blue Jays at the top of the AL wildcard chase.

Center fielder Julio Rodriguez is batting .277 to lead Seattle and has a team-high 133 hits. Third baseman Eugenio Suarez is the leader in home runs with 30 and RBIs with 82, while left fielder Jesse Winker is the leader in on-base percentage at .343. On Wednesday, the Seattle Mariners will send Luis Castillo to the mound. The right-hander is 6-5 with a 2.81 ERA, 141 Ks and 38 BBs.

While the OVER is a solid choice, the play here is Seattle. San Diego starter Mike Clevinger has been hit hard in each of the last two outings allowing nine runs on nine hits across 8 ⅓ innings. Seattle has won 13 of the last 16 versus an opponent with a winning record, eight of the last 10 interleague games and six of the last eight against an opponent from the National League West. Final Score Prediction, Seattle Mariners win 7-2.

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