San Diego Padres at Cincinnati Reds 4/28/22 - MLB Picks & Predictions
Last Updated: 04/27/2022 at 11:19 PM ET

The Great American Ball Park will play host to a Thursday afternoon MLB matchup between the San Diego Padres and the Cincinnati Reds. The Padres (12-7) have won six of their first ten road games and trail NL West Division leading San Francisco by 1.5 games. Last night, Jurickson Profar and Eric Hosmer each went deep to lead San Diego to an 8-5 road victory.
Thirty-one year old southpaw Nick Martinez (0-2 4.30 ERA) will make his fourth start of the season for the Padres. Control has been an issue for Martinez, who has allowed ten walks and five home runs through 14 plus innings.
The Cincinnati Reds have dropped six of their first seven home games and own the worst overall record in the majors. During Wednesday's home loss, Cincinnati went 1-for-10 with runners in scoring position and stranded 11 men on base. SP Vladimir Gutierrez (0-4) gave up six runs in four innings and took the loss for the Reds, who fell to 3-15 overall.
The Reds will turn to twenty-seven year old righty Tyler Mahle (1-2 6.88 ERA) on Thursday. Cincinnati has lost Mahle’s last three starts and he has been tagged for 13 runs over his last 12 innings of work.
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San Diego OF Wil Myers (thumb) was absent from Wednesday’s lineup and is listed as day-to-day. Through 19 games, San Diego ranks 15th in OPS and 10th in runs scored. For the season, Cincinnati ranks 30th in OPS and 30th in runs scored. Take the Reds to win at home. Final Score Prediction, Cincinnati Reds win 5-3.