Pittsburgh Pirates at Chicago Cubs 7/25/22 - MLB Picks & Predictions

Last Updated: 07/24/2022 at 10:22 PM ET

Pittsburgh Pirates at Chicago Cubs 7/25/22 - MLB Picks & Predictions

The Pittsburgh Pirates open a two-game series on the road Monday at Wrigley Field against the Chicago Cubs. Pittsburgh is 40-55 following a 1-0 victory over the Miami Marlins on Saturday. Jose Quintana threw seven shutout innings for the Pirates. Pittsburgh has won two out of the last three and the Pirates are third in the National League Central, 12 games behind the first-place Milwaukee Brewers.

Bryan Reynolds is batting .261 to lead Pittsburgh and the center fielder has team highs in home runs with 15 and on-base percentage at .343. Designated hitter Daniel Vogelbach is the leader in RBIs with 34 and third baseman Ke’Bryan Hayes is the leader in hits with 82. On Monday, the Pittsburgh Pirates will send JT Brubaker to the mound. The right-hander is 2-8 with a 4.02 ERA, 97 Ks and 40 BBs.

Chicago is 37-57 following its 6-2 victory over the Philadelphia Phillies on Saturday. Nico Hoerner hit a home run and later scored the tie-breaking run for the Cubs in the 10th inning when Chicago put five runs across the plate. The Cubs have won three straight. Chicago is fourth in the National League Central, 14 ½ games behind the first-place Milwaukee Brewers.

Nico Hoerner is batting .303 to lead Chicago, while Patrick Wisdom is the leader in home runs with 17 and RBIs with 47. Willson Contreras is the leader in on-base percentage of .372 and Ian Happ is the leader in hits with 92. On Monday, the Chicago Cubs will send Keegan Thompson to the mound. The right-hander is 7-4 with a 3.43 ERA, 75 Ks and 29 BBs.

Pittsburgh starting pitcher JT Brubaker is coming off a strong outing in which the right-hander allowed no runs on three hits across seven innings with nine strikeouts and two walks against the Miami Marlins. Chicago starter Keegan Thompson is coming off a poor outing in which the right-hander allowed five runs on eight hits across just 4 ⅓ innings resulting in an 8-0 loss to the New York Mets. Final Score Prediction, Pittsburgh Pirates win 4-3.

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