Padres at Giants 9/26/18 - MLB Picks & Predictions

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Last Updated: 08/07/2019 at 7:36 AM ET

Padres at Giants 9/26/18 - MLB Picks & Predictions

The San Diego Padres conclude a three-game series on the road Wednesday against the San Francisco Giants. The Padres won the opening game of the series against the Giants 5-0 on Monday. Bryan Mitchell pitched 8 2/3 innings and struck out seven for the win, while Jose Pirela had three hits including a home run.

The loss was the fifth straight for San Francisco and came just a few hours after the Giants announced Bobby Evans was fired as general manager. The Giants have had a disastrous September losing 17 of 21 games. Derek Holland took the loss to fall to 7-9 in the season after allowing eight hits and three runs over five innings. Eric Hosmer leads San Diego with a .250 batting average and a team high in hits with 149. Hunter Renfroe is the team leader in home runs with 25 and RBIs with 67. San Diego has a team batting average of .235 while opposing hitters are averaging .258 at the plate against Padres pitching. On Wednesday, the Padres will send Eric Lauer to the mound. The lefthander this season is 6-7 with an ERA of 4.60, 94 Ks and 45 BBs.

Brandon Crawford leads the Giants with a .256 batting average and has a team high in hits with 133 and RBIs with 54. Evan Longoria leads the team in home runs with 16. San Francisco has a team batting average of .241 while opposing hitters are averaging .249 at the plate against Giants pitching. On Wednesday, the Giants will send Madison Bumgarner to the mound. The lefthander this season is 6-6 with an ERA of 3.20, 103 Ks and 42 BBs.

San Diego has won just 2 of its last 8 games at AT&T Park and the Padres are a disastrous 19-41 over the last 60 games versus teams from the NL West. San Diego is 11 games under .500 on the road and enters this game having lost 6 of its last 10 overall. Final Score Prediction, San Francisco Giants win 6-5.

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