Milwaukee Brewers at San Diego Padres 5/25/22 - MLB Picks & Predictions

Last Updated: 05/24/2022 at 10:45 PM ET

The Milwaukee Brewers complete a three-game series on the road Wednesday against the San Diego Padres. Milwaukee dropped to 26-16 following its 3-2 loss to the Padres in the opening game of the series on Monday. Milwaukee has lost two straight and the Brewers remain first in the National League Central, two games ahead of the St Louis Cardinals. 

Hunter Renfroe is batting .266 to lead Milwaukee and the right fielder has team highs in home runs with nine and hits with a 38. First baseman Rowdy Tellez is the leader in RBIs with 32 and left fielder Christian Yelich is the leader in on-base percentage at .335. On Wednesday, Milwaukee will send Aaron Ashby to the mound. The left-hander is 0-3 with a 3.49 ERA, 34 Ks and 17 BBs.

San Diego improved to 28-14 following its one-run victory over Milwaukee on Monday. Rookie Jose Azocar hit a single to drive in the winning run for Milwaukee on Monday in the 10th inning. The victory was San Diego's fifth straight and seventh in the last eight. The Padres are second in the National League West, a half-game behind the first-place Los Angeles Dodgers.

Third baseman Manny Machado is batting .365 with 8 home runs, 27 RBIs, 58 hits and an on-base percentage of .440 to lead San Diego in each category. Jurickson Profar is second in home runs with five, while Eric Hosmer is second in RBIs with 24. On Wednesday, San Diego will send Yu Darvish to the mound. The right-hander is 4-1 with a 3.91 ERA, 37 Ks and 11 BBs.

San Diego is playing excellent baseball with five consecutive victories through its win over the Brewers on Monday night. San Diego starting pitcher Yu Darvish is coming off an excellent start. Last Thursday, the right-hander allowed six hits and no runs across seven Innings while striking out five and a 2-0 victory over the Philadelphia Phillies. Milwaukee has lost each of its last six when playing against an opponent from the National League West. Final Score Prediction, San Diego Padres win 6-2.

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