Kansas City Royals at St. Louis Cardinals 4/13/22 - MLB Picks & Predictions
Last Updated: 04/12/2022 at 10:20 PM ET

The Kansas City Royals conclude a two-game interleague series on the road Wednesday with the St Louis Cardinals. Kansas City is 2-2 following its 10-7 loss to the Cleveland Guardians on Sunday. The Royals have lost each of the last two games and have allowed a combined 27 runs in the two losses after allowing 17 runs on Saturday and 10 more Sunday. The Royals were off on Monday.
Andrew Benintendi is batting .538 to lead Kansas City and the left fielder has team highs in RBIs with four, hits with seven and on-base percentage at .625. Benintendi is also the only player for Kansas City with a home run. On Wednesday, Kansas City will send Zack Greinke to the mound. The right-hander is 0-0 with a 1.59 ERA, 1 K and 1 BBs.
St.Louis is 2-1 following its 9-4 loss to the Pittsburgh Pirates on Sunday. Nolan Arenado hit a two-run home run for St Louis in the first inning. Cardinals’ starting pitcher Stephen Matz suffered the loss after pitching just three innings and allowing seven runs on nine hits. Tyler O'Neill and Dylan Carlson each had one RBI in the loss for St. Louis. The final game of the four-game series with Pittsburgh was postponed on Monday.
Nolan Arenado is batting .500 to lead St.Louis and the third baseman has team highs in home runs with two, RBIs with seven and hits with six. First baseman Paul Goldschmidt is the leader in on-base percentage at .571. On Wednesday, the St Louis Cardinals will send Jordan Hicks to the mound. Last season in 10 relief appearances, Hicks was 0-0 with a 5.40 ERA, 10 Ks and 10 BBs.
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Kansas City starting pitcher Zack Greinke pitched well in his debut with the Royals allowing one run on five hits in 5 ⅔ innings but did not take part in the decision against Cleveland. Royals left fielder Andrew Benintendi has started the season hot at the plate with seven hits and four RBIs through the first four games. The Royals have won five of the last seven interleague matchups against a right-handed starter. Final Score Prediction, Kansas Royals win 6-3.