Tigers vs Guardians Picks and Prediction – 7/5/2025

By: Jeremy O’Quinn |

Last Updated: 07/04/2025 at 9:21 PM ET

Detroit Tigers at Cleveland Guardians 07/05/25 - MLB Picks & Predictions
Game Start: 7/5/2025, 11:15 PM UTC
Latest Odds: DET -140 ; O/U 9

Tigers vs Guardians Prediction

The Detroit Tigers will be returning to Progressive Field on Saturday, where they will take on the Cleveland Guardians. Get the rest of our free MLB picks here! The Tigers currently sit with a 54-34 record which places them first in the AL Central. Detroit has lost two straight games, as they are coming off an 11-7 loss against Washington. Casey Mize will be the Tigers’ starting pitcher on Saturday, he’s posted a 2.86 ERA to go along with his 8-2 record. Detroit is scoring 5.1 runs per game, while allowing 7.8 hits and 3.9 runs a game.

The Cleveland Guardians have put together a record of 40-45 which places them third in the AL Central. The Guardians come into this series on a seven game losing skid, as they are coming off a 1-0 loss against the Cubs. Logan Allen is set to be Cleveland’s starting pitcher on Saturday, he’s posted a 4.27 ERA to go along with his 5-9 record. The Guardians are putting up 3.6 runs per game, while giving up 4.2 a game

Tigers vs Guardians Pick Analysis

Cleveland is desperate to bring their seven game losing skid, while Tigers also look to shake off consecutive losses. Mize has been incredible on the mound this season, expect his play to help lead the Tigers to the win. Final score prediction, Detroit wins and covers the run line 5-3.

Our Free MLB Pick for Cleveland Guardians vs Detroit Tigers

Detroit Tigers: -1.5