Cleveland Guardians at Chicago White Sox 9/20/22 - MLB Picks & Predictions

Last Updated: 09/19/2022 at 9:04 PM ET

The Cleveland Guardians head to Chicago to take on the White Sox in a three game series. The Guardians are 1st in the AL Central with a 80-67 record. Cleveland beat the Twins on Monday 11-4. Amed Rosario and Josh Naylor each contributed 3 RBI's in the win. The Guardians have won eight of their last ten games. 

Aaron Civale will make his 17th start on the mound for the Guardians. Civale is 2-6 on the season with 75 innings pitched. Civale has 75 strikeouts and carries a 5.40 ERA. Civale pitched 6.1 innings in his last start allowing 4 runs and 4 hits. The Cleveland Guardians are allowing 4 runs against per game which ranks 9th best in the MLB. 

The Chicago White Sox head into Tuesday's game riding a two game win streak. The White Sox also scored 11 runs in their last game when they beat the Tigers on Sunday. Andrew Vaughn led the way with 4 RBI's and a home run. Chicago has won seven of their last ten games. 

Dylan Cease will make his 30th start on the mound for the White Sox. Cease is 14-7 with 167 innings pitched. Cease has 214 strikeouts and carries a 2.16 ERA. Cease pitched 5 innings in his last start allowing 3 runs and 6 hits. The Chicago White Sox have allowed 152 home runs this season which is 12th best in the league. 

The Cleveland Guardians show value whenever they are an underdog. The Guardians have won five of their last six road games heading into Chicago. Cleveland seeks revenge after losing their last meeting to Chicago. Grab the underdog. Final Score Prediction, Cleveland Guardians win 5-4. 

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