Chicago White Sox at Minnesota Twins 9/28/22 - MLB Picks & Predictions

Last Updated: 09/27/2022 at 11:01 PM ET

Chicago White Sox at Minnesota Twins 9/28/22 - MLB Picks & Predictions

The Chicago White Sox play the second game of a three-game series on the road Wednesday against the Minnesota Twins. Chicago is 76-77 following a 4-1 loss to the Detroit Tigers on Sunday. Chicago has lost six straight and the White Sox are 10 games behind first place in the American League Central. Chicago is 7 ½ games behind the third and final AL wildcard spot and on the verge of being eliminated from postseason contention.

First baseman Jose Abreu is batting .304 to lead Chicago and has team highs in RBIs with 73, hits with 176 and on-base percentage at .377. Right fielder Andrew Vaughn is the leader in home runs with 17. On Wednesday, the Chicago White Sox will send Johnny Cueto to the mound. The right-hander is 7-9 with a 3.15 ERA, 91 Ks and 32 BBs.

Minnesota dropped to 74-79 following its 10-3 loss on Sunday to the Los Angeles Angels. The Twins are 1-6 over the last seven and Minnesota has dropped nine of the last 11. The Twins are third in the American League Central, 12 games behind first-place. Minnesota is 9 ½ games behind the third and final AL wildcard spot and will likely be eliminated from playoff contention by the time this game is played. 

First baseman Luis Arraez is batting .313 to lead Minnesota and is the team leader in hits with 164 and on-base percentage at .371. Shortstop Carlos Correa is the active leader in home runs with 21 and first baseman Jose Miranda is the leader in RBIs with 64. On Wednesday, the Minnesota Twins will send Josh Winder to the mound. The right-hander is 4-5 with a 4.20 ERA, 39 Ks and 17 BBs. 

Chicago has struggled over the last week, losing each of the last six and the White Sox have lost five of the last seven versus an opponent with a losing record. In contrast, Minnesota has won nine of the last 12 at home versus an opponent with a losing record. Chicago starting pitcher Johnny Cueto has been hit hard in each of the last two outings allowing 11 runs on 16 hits across 10 ⅔ innings, resulting in Chicago losing each of the two. Final Score Prediction, Minnesota Twins win 6-4.

Download the Picks and Parlays Mobile App

Get A free VIP Pick Daily!