Chicago White Sox at Boston Red Sox 4/16/21 - MLB Picks & Predictions

Last Updated: 04/16/2021 at 8:56 AM ET

The Chicago White Sox have struggled through the first week of the season coming into this game 6-7 after losing 2 of the last 5 games. Dylan Cease (0-0 3.86 ERA) will get the ball for the White Sox Friday night on the road. Cease has given up 4 runs on 9 hits, while striking out 9 batters in 9.1 innings pitched over the first 2 starts of the year.

The White Sox have the 5th best offense in the MLB scoring 5.25 runs on 7.92 hits per game. Yermin Mercedes leads the Chicago offense batting .476 on the season. Adam Eaton boasts a team high 3 homers to go along with a team leading 10 RBI's.

The Red Sox are on a tear coming in 9-4 on the season after winning 9 of the last 10 games played. Boston will turn to Nick Pivetta (2-0 3.27 ERA) to get the ball Friday night at home. Pivetta has looked great on the year giving up 4 runs on 9 hits across 11 inning pitched over 2 games this year.

Boston is the 2nd ranked offense in the league scoring 6 runs per game, while boasting a league high 9.92 hits. J.D. Martinez does it all for the Boston offense with team highs in every offensive category, while boasting a .378 average with 16 RBI's through 13 games.

The Red Sox are the hottest team in baseball right now despite losing on Thursday to the Twins. Chicago has struggled this year mainly offensively as runs have come at a premium. Even with a good pitcher on the mound for Chicago this Boston lineup will be able to post runs in route to a win. The Red Sox are by far the better team here and it should show from the jump. Final Score Prediction, Boston wins 6-3.

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