Chicago Cubs at St. Louis Cardinals 7/21/21 - MLB Picks & Predictions

In Wednesday night baseball on ESPN,  the Chicago Cubs and the St. Louis Cardinals will battle from Busch Stadium. The Cubs (47-48) have dropped 31 of their first 50 road games and are tied with St. Louis for third place in the NL Central Division standings. Last night, Chicago rallied for six runs in the ninth innings to score a stunning 7-6 road victory against St. Louis.

Thirty-one year old righty Kyle Hendricks (12-4 3.65 ERA) will take the mound for the Cubs in this matchup. Chicago has won Hendricks’ last two starts and he has allowed three runs over his last 12 plus frames.

The St. Louis Cardinals are six games above .500 at home and are 8.5 games behind first place Milwaukee. On Tuesday, All-Star 3B Nolan Arenado hit his 18th home run and Jose Rondon added a pinch-hit solo shot. SP Johan Oveido allowed one run across five solid frames and did not factor in the decision for the Cardinals (47-48).

Thirty-nine year old righty Adam Wainwright (7-6 3.71 ERA) will take the ball for the Cardinals on Wednesday. Last time out, Wainwright gave up four runs in six innings during a 7-2 home loss versus San Francisco.