Chicago Cubs at Cincinnati Reds 5/25/22 - MLB Picks & Predictions
Last Updated: 05/24/2022 at 10:45 PM ET

The Chicago Cubs will play the third game of a four-game series on the road Wednesday against the Cincinnati Reds. Chicago improved to 17-24 following its 7-4 victory over the Reds in the opening game of the series on Monday. Ian Happ and Patrick Wisdom each hit the three-run home runs in the victory. Chicago is fourth in the National League Central, 8 ½ games behind the first place Milwaukee Brewers.
Ian Happ is batting .286 to lead Chicago and the center fielder has team highs in hits with 36 and on-base percentage at .399. Third baseman Patrick Wisdom is the leader in home runs with 10 and RBIs with 23. On Wednesday, the Chicago Cubs will send Kyle Hendricks to the mound. The right-hander is 2-4 with a 4.89 ERA, 35 Ks and 17 BBs.
Cincinnati dropped to 12-29 following its three-run loss to Chicago on Monday. The Reds have lost three out of the last 24. Cincinnati is 28th in team batting average at .217 and on the mound, the Reds are last 10 the team ERA at 5.64. Cincinnati is last in the National League Central, 13 ½ games behind the first-place Milwaukee Brewers.
Right fielder Tyler Naquin is batting .256 to lead Cincinnati, while third baseman Brandon Drury is the leader in home runs with seven and RBIs with 22. Left fielder Tommy Pham is the leader in hits with 31 and on-base percentage at .331. On Wednesday, the Cincinnati Reds will send Luis Castillo to the mound. The right-hander is 0-2 with a 4.60 ERA, 12 Ks and 4 BBs.
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Chicago starting pitcher Kyle Hendricks is coming off his worst start of the season. Last Friday the right-hander allowed seven runs on eight hits across only five innings resulting in a 10-6 loss to the Arizona Diamondbacks. Although Cincinnati starting pitcher Luis Castillo is 0-2, the right-hander gave up only two runs on two hits across six innings last time out in a 2-1 loss to Toronto. Chicago has lost five of the last seven played in Cincinnati. Final Score Prediction, Cincinnati Reds win 4-2.