Boston Red Sox at Cincinnati Reds 9/21/22 - MLB Picks & Predictions

Last Updated: 09/20/2022 at 11:09 PM ET

Boston Red Sox at Cincinnati Reds 9/21/22 - MLB Picks & Predictions

The Great American Ball Park will play host to a Wednesday night MLB interleague battle between the Boston Red Sox and the Cincinnati Reds. The Red Sox (72-75) are three games below .500 on the road and are stuck in the AL East Division basement. Last night, All-Star 3B Rafael Devers hit a two-run blast to power Boston to a 5-3 road victory against Cincinnati.

Boston manager Joey Cora has yet to name a starting pitcher for this game. The Red Sox rank in the bottom third of the majors with a 4.45 team ERA and have logged 42 quality starts.

The Cincinnati Reds have lost eight of their last ten games and have been unable to overcome their dreadful 3-22 start to the year. On Tuesday, Cincinnati batters went 0-for-9 with runners in scoring position and left ten men on base. SP Nick Lodolo (4-7) gave up three runs in five innings and took the loss for the Reds, who fell to 58-90 on the year.

Thirty-four year old righty Chase Anderson (1-3 6.43 ERA) will make his fifth start of the season for the Reds. Last time out, Anderson allowed one run in five innings during a 3-2 road victory against St. Louis.

Boston 2B Trevor Story (heel) has missed six consecutive games and remains listed as day-to-day. Through 147 games, Boston ranks 9th in OPS and 9th in runs scored. For the season, Cincinnati ranks 24th in OPS and 20th in runs scored. Take the over. Final Score Prediction, Boston Red Sox win 7-5.

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